Effect of chronic administration of Aloe vera extract on plasma biochemistry in rabbits

Due to excessive use, synthetic medicines are going to be expensive and resistant, their residues accumulate in blood, that is why slowly and gradually they become resistant. Alternatives to synthetic medicines are herbal medicines that are cheap, with minimum or no side effect. Previous studies found that liquid extract of Aloe vera plant proved beneficial for animal’s health as it has immune-modulating, hypolipidemic, hypoglycemic and haematinic effects. The aim of this study was to investigate the effect of A. vera extract on plasma biochemistry. A total of twenty (n = 20) male rabbits were selected and divided into 4 groups; P, Q, R and S with five (n = 5) in each group. The group P was kept as control while group Q, R and S were given oral A. vera extract at the dose of 200, 300 and 400 mg/kg body weight, respectively daily for 21 days. Blood samples were taken on various days; 0, 7, 14 and 21 of treatment. Research has found that A. vera significantly (p < 0.05) decrease cholesterol level, that is indication that A. vera has influence on adipose tissues.