A Pragmatic Perspective of the Initial Stages of the Contact Killing of Bacteria on Copper-Containing Surfaces

Sacher, Edward (2022) A Pragmatic Perspective of the Initial Stages of the Contact Killing of Bacteria on Copper-Containing Surfaces. Applied Microbiology, 2 (3). pp. 449-452. ISSN 2673-8007

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Abstract

A consideration of the outer structures of Gram-positive and Gram-negative bacteria, and of the surface contaminants present on Cu-containing substrates, has led to the identification of Cu2O as a potent antimicrobial. In the presence of adsorbed water, the hydrated form ionizes to CuI-O−, which is capable of degrading the protective polysaccharide layer of the outer lipopolysaccharide membranes of Gram-negative bacteria; it is equally capable of attacking the peptidoglycan lattices present in both Gram-positive and Gram-negative bacteria. This Perspective underlines the importance of CuI-O− in the early stages of contact killing, and points to information, still lacking, that would optimize contact killing and lead to broader applications in the therapeutic management of bacterial infections.

Item Type: Article
Subjects: STM Library > Biological Science
Depositing User: Managing Editor
Date Deposited: 01 Feb 2023 06:44
Last Modified: 17 May 2024 09:37
URI: http://open.journal4submit.com/id/eprint/376

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