LARVICIDAL ACTIVITY OF CRUDE EXTRACTS AND FRACTIONS OF NATIVE PLANTS AGAINST Aedes aegypti L. AND Culex quinquefasciatus say. (DIPTERA: CULICIDAE)

Several millions of people get affected by mosquito-borne sicknesses every year, and hence mosquito-borne sicknesses are regarded as major public health diseases. The vector mosquito Aedes aegypti transmits chikungunya fever, dengue fever, yellow fever viruses and Culex quinquefasciatus transmits filarial nematode and cause filariasis. In the present study, In the present study, the leaves of Cymbopogon citratus, Azadirachta indica, Tagetes erecta, Eucalyptus deglupta and Syzygium aromaticum were screened on Cx. quinquefasciatus and Ae. aegypti mosquito larvae. Ethanol extract of Eucalyptus deglupta leaves was found to be very active and the LC50 and LC90 results were 63.54 ppm, 96.90 ppm against Cx. quinquefasciatus and 72.19 ppm, 137.90 ppm against Ae. aegypti larvae, respectively. Eight fractions were obtained from the active extract and fraction 7 was identified to be very effective. The LC50 and LC90 results of fraction-7 were 5.07 ppm, 12.64 ppm against Cx. quinquefasciatus larvae and 5.50 ppm, 17.18 ppm against Ae. aegypti larvae, respectively. The active ethanol extract of Eucalyptus deglupta leaves may be used in mosquito control activities.