Rao, R. Nageswara and Ravikumar, V. and Reddy, L. Shiva Shankar and Madhuri, D. and Yellasubbaiah, N. and Kumar, S. V. Suresh and Gopal, N. Madana and Indradev, S. and Vinay, S. and Mahesh, S. and Kumar, P. Ajay (2023) Method Development and Validation for the Estimation of Bortezomib in Pure and Its Pharmaceutical Tablet Dosage form by UV Spectroscopy. In: Novel Aspects on Pharmaceutical Research Vol. 1. B P International, pp. 154-164. ISBN 978-81-19217-16-8
Full text not available from this repository.Abstract
Background: Bortezomib is an anti-cancer medication used to treat multiple myeloma and mantle cell lymphoma.
Methods: The UV Spectroscopy method for analysis of bortezomib was developed and validated as per ICH guidelines. The estimation of bortezomib in the pure and tablet dosage form was carried out at the maximum absorbance at 365 nm.
The Results: The method was found to be linear and obeys beers law in the concentration range 5-25µg/ml with a correlation coefficient 0.999, the developed method was validated as per ICH guidelines and was found to be accurate and precise.
Conclusion: A rapid novel precise and accurate UV Spectroscopy method was developed and validated and can be used for regular analysis for the estimation of bortezomib.
| Item Type: | Book Section |
|---|---|
| Subjects: | STM Library > Medical Science |
| Depositing User: | Managing Editor |
| Date Deposited: | 29 Sep 2023 09:48 |
| Last Modified: | 29 Sep 2023 09:48 |
| URI: | http://open.journal4submit.com/id/eprint/2705 |
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