Antibacterial Effect of Rose Leaves and Petals Extract Along with Antibiotics on Escherichia coli: An In vitro Evaluation

The present study was planned to evaluate the antibacterial effect of petals and leaves ex- tract of rose along with resistant antibiotics against Escherichia coli isolated from different clinical samples. Roses have been studied for their medicinal properties in addition to their fragrance. In ancient medicine, R. damascena was used for the treatment of abdominal and chest pain, menstrual bleeding, digestive problems, depression, grief, nervous stress, ten,sion, skin problems and headaches. This is a hospital based prospective study from April to September 2019.Escherichia coli isolated from diverse clinical samples along with resistance antibiotics.All resistant isolates were tested along with hibiscus Rosa sinensis extract both leaves and petals ex-tract with resistant antibiotics. The findings showed that out of total 51, 35 (68.63%) were resistant E. coli isolates to different antibiotics and 85.72% were from urine samples. Individually, both extracts showed an increase in zone size with many resistant antibiotics. Antibiotics like ampicillin, cefotaxime, cotrimaxazole, cefuroxime, piperacillin, gentamycin showed more enhancement with rose petal extract than leaves. While antibiotic like levofloxacin (5%) showed enhancement only with leaves extract and not with the petals extract.

it is concluded that rose petals and leaves extracts have antibacterial activity against Escherichia coli along with antibiotics. The application of herbal extracts can decrease the use of antimicrobial agents and have excellent potential in reducing the antimicrobial resistance of E. coli.