A Short Review of Coronary Artery Lesions in Children

Kawasaki disease may be a systemic inflammatory disease with a predominantly intrinsic immune disorder due to exposure of genetically susceptible individuals to various infections and/or environmental triggers. The disease is prevalent in patients with autoimmune diseases or Kawasaki disease in childhood, in men with dyslipidemia, in men with hypertension, in men who are chronic smokers, and can be triggered by infections with autoimmune abnormalities and emotional agitation. Clinicians need to have a better understanding of the immunological mechanisms of the disease and to broaden their thinking about diagnosis and treatment to avoid misdiagnosis and underdiagnosis.