Sclerosing Central Mucoepidermoid Carcinoma: Rare Case Series and Review

Mucoepidermoid carcinoma (MEC) comprises around 30% of all salivary gland malignancies, making it a preeminent threatening tumour of the salivary glands. Numerous histologic variants with a great extent of separation have been portrayed. Sclerosing MEC (SMEC) has been portrayed as an uncommon subtype, that can be misdiagnosed as a generous receptive condition or low-grade non-SMEC malignancy. The sclerosing variant of central or intraosseous MEC is extremely rare and no cases are reported to date. We report 2 cases of Sclerosing central MEC, in which histologic examination demonstrated relatively nicely-circumscribed, nonencapsulated tumours composed of significant valuable sclerosis and scattered epithelial islands of low-grade MEC. Within the 2nd case, the tumour confirmed comparable sclerotic stroma; but the epithelial component became of intermediate grade. A Mayer mucicarmine stain and PAS stain were fine in each case and discovered plentiful intracytoplasmic mucin. An analysis of sclerosing crucial mucoepidermoid carcinoma was made. A whole resection of the tumour was executed in both instances and remained sickness free to date.