Updates in Diagnosis and Management of Ectopic Pregnancy

Morcy, Hesham Mohamed Hamad and Abdullah, Luluah Maan Ramadan and Alenezi, Maryam Mohammed M. and Sultan F., Almutairi, Fai and Almadani, Sama Abdulfattah M. and Raghad Khalid, R. Alruwaili, (2022) Updates in Diagnosis and Management of Ectopic Pregnancy. Journal of Pharmaceutical Research International, 34 (22B). pp. 31-38. ISSN 2456-9119

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Abstract

Ectopic pregnancy (EP) occurs when the conceptus becomes embedded and matures beyond the endometrial cavity, resulting in the foetus' mortality.

Ectopic pregnancy can become a lifethreatening issue if it is not diagnosed and treated promptly. The most common symptoms of an unruptured ectopic pregnancy are first-haemorrhage and abdominal pain.

Although these symptoms can also occur in intrauterine pregnancy and spontaneous abortion, when a pregnant woman shows them, clinicians should suspect ectopic pregnancy. Methotrexate, a folic acid antagonist, has been extensively studied in medicine. Methotrexate inhibits dihydrofolate reductase, causing trophoblastic cells to divide rapidly and reducing tetrahydrofolate levels (a cofactor for deoxyribonucleic acid and ribonucleic acid formation).

Item Type: Article
Subjects: STM Library > Medical Science
Depositing User: Managing Editor
Date Deposited: 16 Feb 2023 07:35
Last Modified: 15 May 2024 09:32
URI: http://open.journal4submit.com/id/eprint/1351

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